The Neuropathology Core (NPC) focuses on the coordination of autopsies for patients enrolled in the CADRC. This includes the final diagnostic study, storage, and distribution of fixed and frozen brain tissue from longitudinally characterized patients enrolled in the CADRC.
The NPC is located at Case Western Reserve University, within the National Prion Disease Pathology Surveillance Center (NPDPSC). The NPDPSC has over two decades of experience with coordinating autopsies, collecting, characterizing, storing and distributing tissues from suspected prion disease cases across the U.S.
We work closely with the CADRC Clinical Core (CC) to enroll patients in the brain donation program. Our autopsy coordinators assist families in obtaining the necessary data for a smooth autopsy coordination effort. The tissues are then tested and diagnosed per NIA-AA criteria.
Researchers may also request tissue through the NPC biobank. Requests should be directed to NPC@ClevelandADRC.org
Dr. Mark Cohen, Director (Co-Director, National Prion Disease Pathology Surveillance Center)
Dr. Brian Appleby, Co-Director (Director, National Prion Disease Pathology Surveillance Center)
Dr. Jim Leverenz, Additional Neuropathology Review
Katie Glisic, Research Administrator
Danielle Jordan and Meghan Lewis, Autopsy Coordinators
Aaron Koeth, UH Mortician’s Office
UH & NPDPSC histology staff
For more information on Brain Donations through the CADRC, see our FAQ page: https://clevelandadrc.org/cadrc-brain-donation-faq/