Cleveland Alzheimer’s Disease Research Center


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The Cleveland Alzheimer’s Disease Research Center (CADRC) is a National Institute on Aging Center which has the goal of increasing the speed of research being done on aging-related brain disorders. A key activity of the CADRC is a multi-site, observational study in which older individuals both with and without dementia will be followed over time. Participants will be asked to undergo bio-specimen collection, imaging procedures, and cognitive testing on an annual basis. This readily-available data will be used to advance national-level future research, including therapeutic trials.


CADRC Investigator News

Photo of Andrew Pieper
Andrew Pieper MD
Translational Therapeutics Core Leader

“There is a growing body of evidence in the field that Alzheimer’s disease develops much earlier than previously thought, most likely decades before our current ability to clinically diagnose the condition,” said study co-author Andrew A. Pieper.

New Alzheimer’s disease pathway discovered, providing earlier target for potential therapies – The Daily


“Our goal is to provide supportive intervention for those caring for someone with dementia, particularly during these transitional periods of caregiving for persons with dementia,” Zauszniewski said.

Nursing’s Jaclene Zauszniewski awarded $2.6M grant to study stress management in caregivers of people with dementia – The Daily
Jaclene A. Zauszniewski, PhD, RN-BC, FAAN
OREC Team Member

Photo of elderly couple and young caregiver walking in the nature

We have a number of exciting opportunities to learn more and get involved

Close up of male carer holding hands of senior woman, home caregiver showing support for elderly patient.

CADRC is a collaboration between Case Western Reserve University, Cleveland Clinic, University Hospitals and the Louis Stokes Cleveland VA Medical Center