Cleveland Alzheimer’s Disease Research Center

On June 7, 2021, the FDA approved aducanumab to treat patients with Alzheimer’s disease .
For more information about this new treatment, please click here.

The Cleveland Alzheimer’s Disease Research Center (CADRC) is a National Institute on Aging Center which has the goal of increasing the speed of research being done on aging-related brain disorders. A key activity of the CADRC is a multi-site, observational study in which older individuals both with and without dementia will be followed over time. Participants will be asked to undergo bio-specimen collection, imaging procedures, and cognitive testing on an annual basis. This readily-available data will be used to advance national-level future research, including therapeutic trials.

Upcoming Event

Managing Behavior Changes with
Alzheimer’s and Other Dementias
Join us for this live webinar
Wednesday, August 4, 2021
Noon – 1 p.m.
Register for this webinar at 
If you need assistance with registration or have questions please call Cleveland Clinic Lou Ruvo Center for Brain Health Research at 216.445.9009 or email
No computer? No problem. Call 216.445.9009 to learn how to join the webinar with audio only.

CADRC Investigator News

Lynn Bekris, PhD, Associate Staff at the Cleveland Clinic Genomic Medicine Institute and leader of the CADRC Biomarker Core, has been awarded a three-year, nearly $300,000 grant from the Aging Mind Foundation to study inflammatory factors involved in the early stages of Alzheimer’s disease (AD) in order to better understand the underlying cause of AD and inform novel therapeutic strategies.
Photo of Andrew Pieper
Andrew Pieper MD
Translational Therapeutics Core Leader

“There is a growing body of evidence in the field that Alzheimer’s disease develops much earlier than previously thought, most likely decades before our current ability to clinically diagnose the condition,” said study co-author Andrew A. Pieper.

New Alzheimer’s disease pathway discovered, providing earlier target for potential therapies – The Daily

“Our goal is to provide supportive intervention for those caring for someone with dementia, particularly during these transitional periods of caregiving for persons with dementia,” Zauszniewski said.

Nursing’s Jaclene Zauszniewski awarded $2.6M grant to study stress management in caregivers of people with dementia – The Daily

Jaclene A. Zauszniewski, PhD, RN-BC, FAAN
OREC Team Member

Photo of elderly couple and young caregiver walking in the nature

We have a number of exciting opportunities to learn more and get involved

Close up of male carer holding hands of senior woman, home caregiver showing support for elderly patient.

CADRC is a collaboration between Case Western Reserve University, Cleveland Clinic, University Hospitals and the Louis Stokes Cleveland VA Medical Center

For COVID-19 (The Novel Coronavirus) Information for Caregivers please click here.

Para obtener información sobre COVID-19 (El nuevo coronavirus) para cuidadores, haga clic aquí.