The CADRC is joining centers around the nation to conduct a brain imaging research study—CLARiTI
The Cleveland Alzheimer’s Disease Research Center (CADRC) is joining centers around the nation to conduct a brain imaging research study to identify how Alzheimer’s disease and related dementias develop.
The ADRC Consortium for Clarity in ADRD Research Through Imaging (CLARiTI) is one of the nation’s largest studies to help researchers understand the causes of Alzheimer’s and related dementias.
The goal is to determine how far in advance symptoms of Alzheimer’s disease and related dementias begin. We anticipate that this study will improve our ability to diagnose these diseases.
Dr. Frank DiFilippo,
CADRC Principal Investigator,
CLARiTI
This study seeks to identify different possible causes of dementia that may be present in an individual, and that may contribute to current or future cognitive symptoms. We know that Alzheimer’s doesn’t typically occur by itself – it very often has multiple origins. This study is unique and important because it will look at multiple causes. We’re also working to include people from all backgrounds so that we can develop better tools and treatments for more people.
Research participants will be asked to complete an Amyloid PET scan, Tau PET scan, MRI scan, and blood draw. They will also have the option of completing an FDG PET scan to help us learn more about the brain. Participants in the study will be asked to undergo scans and other assessments when they enroll in the study and repeat the procedures two years later.
During a PET scan, a research participant rests on the bed of the scanner with their head in a large hole, as shown above.
CLARiTI will begin enrolling patients beginning the summer of 2025 and for the next two years.
